MANFAAT AGEL UMI DAN FUCOIDAN!!

THE BENEFITS OF AGEL UMI* & FUCOIDAN

Seaweeds are a part of the diet in many cultures and fucoidan-containing species have been used traditionally for a variety of therapeutic purposes. Fucoidan contains an abundance of immune-modulating constituents known as polysaccharides. These unique and complex sulfated polysaccharides are not found in other seaweeds or land plants, and have been shown to mediate a variety of significant biological effects on mammalian cells in laboratory research. Research also suggests that fucoidan may possess significant antioxidant activity.

By taking UMI every single day, you are helping to build your immune system. Fucoidan has been scientifically proven to enhance immunity and cellular health to the point where it helps heal wounds, supports normal blood pressure, detoxifies the body against heavy metals, helps prevent the common cold and flu. These are just a few of the following benefits:

Membantu Mengekalkan Sistem Imun Yang Tinggi
[Help Maintain a Strong Immune System]

Fucoidan supports the immune system in a number of different ways. Some research suggests that it may cause an increase in the number of circulating mature white blood cells in the body, which are an integral part of the body's natural immune system. The findings from other studies suggest that fucoidan supports the immune system by improving phagocytosis and activating other important immune responses. These processes act together to destroy bacteria, viruses and other foreign particles by multiple blood 'scavenger' cells.

Menggalakkan Kesihatan Sistem Percernaan Yang Optimum
[Promotes Optimal Gastrointestinal Health]

The number of people suffering from gastric diseases is rapidly increasing around the world as more and more people are consuming foods with more fat content and less dietary fibre. Once in the stomach, fucoidan attaches to the stomach lining where it has a protective effect. In addition, it stimulates the stomach lining to regulate the inflammatory process and also to 'self-repair' damaged tissue. Fucoidan, because of its immune promoting and inflammation modulating activity, is a tremendous aid in maintaining proper gastrointestinal function and health.

Membantu Menjana Semula Sel Badan dan Meningkatkan Umur
[Regenerate Cells and Increase Life Span]

Much of the research that has been done on fucoidan has been focused on its ability to regenerate cells. Studies have shown that fucoidan helps support mobilisation of stem cells that enable the body to replace dead cells thereby enabling tissue and organ regeneration. In addition, fucoidan helps slow symptoms of the aging process. In study after study, fucoidan has shown itself to be beneficial in the fight for a longer, healthier life.

Menyokong Sistem Peredaran Darah dan Fungsi Kesihatan Umum
[Support the Circulatory System & Health Functions]

Fucoidan has also been shown to help maintain healthy blood flow and cardiac functions, thereby supporting the circulatory system. Increased blood flow helps all of our organs work more efficiently and helps us to feel better and healthier. Efficient functioning of our vital organs can help us prolong the effects of 'wear and tear' of the normal aging process. Additionally, one study suggested that fucoidan helps to slow the absorption rate of glucose, or sugar, into the blood stream. A slower absorption rate leads to a more regulated blood sugar level.

Mengekalkan Paras Kolesterol Yang Normal
[Maintain Healthy Cholesterol Levels]

The process of cholesterol formation is in the liver. Our bodies produce a 'good' cholesterol (HDL) and a 'bad' cholesterol (LDL). Optimum health is achieved when we can maintain lower levels of the LDL, and sufficient levels of the HDL. There is some evidence to suggest that fucoidan can help us to maintain healthy levels of cholesterol by influencing the metabolic activity in the liver where fatty acids are processed. In addition, because fucoidan is a dietary fibre, it absorbs cholesterols contained in foods allowing them to be discharged from the body. This suppresses cholesterol elevations related to dietary intake of foods high in cholesterol.

Membantu Menyokong Fungsi Sendi Yang Sihat
[Help Support Healthy Joint Functions]

For many of us in the United States and throughout the world, healthy joints and cartilage are daily concerns. Arthritis and joint pain can be a bothersome and sometimes debilitating. Among its many properties, fucoidan has been hailed as a natural answer to joint health. Fucoidan supports proper joint functions and cartilage health by modulating some of our body's inflammatory and immune processes.

Membantu Mempercepatkan Penghapusan Sel Merbahaya
[Assist in Inducing the Elimination of Harmful Cells]

Fucoidan may also prove helpful in eliminating harmful cells, including those that are related to some cancers. This is accomplished through a process called apoptosis. Apoptosis is technical term for the process of a cell 'bursting' and therefore dying. Sulphated polysaccharides like fucoidan have been shown to assist in inducing apoptosis, which is a natural proess where living organisms eliminate harmful cells and render the genetic blueprint (DNA) of harmful cells useless. Additionally, some research suggests that fucoidan may have an effect on cancer growth by suppressing the generation of new blood vessels around cancer cells, cutting off their nutrient supply.

RUJUKAN UMI
[UMI References]

1: Antibacterial and immunomodulating activity of fucoidan, Zapopozhets TS, Besednova NN, Loenko IuN. Antibiot Khimioter. 1995 Feb;40(2):9-13.

2: Immunostimulating and anticoagulating activity of fucoidan from brown algae Fucus evanescens of Okhotskoe sea. Kuznetsova TA, Zaporozhets TS, Besednova NN, et al. Antibiot Khimioter. 2003;48(4):11-3.

3: Sulfated Glycans Induce Rapid Hematopoietic Progenitor Cells Mobilization: Evidence for Selectin-dependent and Independent Mechanisms. Frenette PS, Weiss L. Blood, 2000 Oct 1 96(7):2460-8

4: Fucoidan is a non-anticoagulant inhibitor of intimal hyperplasia. McCaffrey TA, Falcone DJ, Borth W, Brayton CF, Weksler BB. Biochem Biophys Res Commun. 1992 Apr 30;184(2):773-81.

5: Fibrinolytic and anticoagulant activities of highly sulfated Fucoidan. Soeda S, Sakaguchi S, Shimeno H, Nagamatsu A. Biochem Pharmacol. 1992 Apr 15;43(8):1853-8.

6: Potential Antioxidant Capacity of Sulfated Polysasccharides From the Edible Brown Seaweed Fucus Vesiculosus. Ruperez P. Ahrazern O. Leal JA Agrie Food Chem. 2002 Feb 13;50(4):840-5

7: Anticoagulant properties of a Fucoidan fraction. Colliec S, Fischer AM, Tapon-Bretaudiere J, Boisson C, Durrand P, Jozefonvicz J. Thromb Res. 1991 Oct 15;64(2):143-54.

8: Intravascular granulocyte aggregates caused by the selectin-binding carbohydrate fucoidan in pig kidneys. Dittrich S, Lippek F, Gratopp A, Grosse-Siestrup C, Lange PE, Buhrer C. Clin Exp Pharmacol Physiol. 2002 Oct; 29 (10): 909-14

9: Hepatic fatty acid oxidation enzyme activities are stimulated in rats fed the brown seaweed. Murata, M. et al. Journal of Nutrition, 1999 Jan:29(1):146-51.

10: Effects of the anti-inflammatory compounds castanospermine, mannose-6-phosphate and fucoidan on allograft rejection and elicited peritoneal exudates. Bartlett MR, Warren HS, Cowden WB Parish CR Immunol Cell Biol. 1994 Oct; 72(5):367-74

11: Immunomodulating activity of arabinogalactan and Fucoidan in vitro. Choi EM, Kim AJ, Kim YO, Hwang JK. J Med Food. 2005 Winter;8(4):446-53.

12: Fucoidan a sulfated polysaccharide from brown algae is a potent modulator of connective tissue proteolysis. Senni K, Gueniche F, Foucault-Bertaud A, Igondjo-Tchen S, Fioretti F, Colliec-Jouault S, Durand P, Guezennec J, Godeau G, Letourneur D. Arch Biochem Biophys. 2006 Jan 1;445(1):56-64.

13: Antitumor activity and immune response of Mekabu fucoidan extracted from Sporophyll of Undaria pinnatifida. Maruvama H, Tamauchi H, Hashimoto M, Nakano T. In Vivo. 2003 May-Jun;17(3):245-9

14: Antitumor activity and immunological properties of marine algal polysaccharides, especially fucoidan, prepared from Sargassum thunbergii of Phaeophyceae. Itoh H. Noda H, Amano H, Zhuang C, MizunoT, Ito H Anticancer Res. 1993 Nov-Dec;13(6A):2045-52

15: Fucoidan extracted from Cladosiphon okamuranus Tokida induces apoptosis of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells. Haneji K, Matsuda T, Tomita M, Kawakami H, Ohshiro K, Uchihara JN, Masuda M, Takasu N, Tanaka Y, Ohta T, Mori N. Nutr Cancer. 2005;52(2):189-201.

16: Antitumor and antiproliferative effects of fucan extracted from ascophyllum nodosum against a non-small-cell bronchopulmonary carcinoma line. Riou D, Colliec-Jouault S, Pnczon du Sel D, Bosch S, Siavoshian S, Le Bert V, Tomasoni C, Sinquin C, Durand P, Roussakis C. Anticancer Res. 1996 May-Jun;16(3A):1213-8.

17: Antitumor activity and immunological properties of marine algal polysaccharides, especially fucoidan, prepared from Sargassum thunbergii of Phaeophyceae. Itoh H. Noda H, Amano H, Zhuang C, MizunoT, Ito H Anticancer Res. 1993 Nov-Dec;13(6A):2045-52

18: Antitumor active fucoidan from the brown seaweed, umitoranoo (Sargassum thunbergii). Zhuang C. et al. Biosci Biotechnol Biochem, 1995 Apr:59(4):563-7.

19: Antibacterial and immunomodulating activity of Fucoidan. Zapopozhets TS, Besednova NN, Loenko IuN. Anitbiot Khimoioter. 1995 Feb;40(2):9-13.

20: Pentosan polysulfate, a sulfated oligosaccharide, is a potent and selective anti-HIV agent in vitro. Baba M, Nakajima M, Schols D, Pauwels R, Balzarini J, De Clercq E. Antiviral Res. 1988 Sep;9(6):335-43.

21: Anitviral properties of Fucoidan fractions from Leathesia difformis. Feldman SC, Reynaldi S, Stortz CA, Cerezo AS, Damont EB. Phytomedicine. 1999 Nov;6(5):335-40.

22: Fucoidan derived from Cladosiphon okamuranus Tokida ameliorates murine chronic colitis through the down-regulation of interleukin-6 production on colonic epithelial cells, Matsumoto S.,Nagaoka M, Hara T. Kimura-Takagi I, Mistsuvama K. Clinical and Experimental Immunology. June 2004, vol. 136, no.3 pp. 432-439(8)

23: The Polysaccharide Fucoidan Inhibits the Antibiotic-induced Inflammatory Cascade in Experimental Pneumococcal Meningitis, Granert C. Raud J, Lindquist L, Clinical and Diagnostic Laboratory Immunology, May 1998, 5(3): 322-4

24: Potential Antioxidant Capacity of Sulphated Polysaccharides From the Edible Brown Seaweed Fucus Vesiculosus. Ruperez P, Ahrazem O, Leal JA. Agric Food Chem. 2002 Feb 13; 50(4):840-5

25: Intravascular granulocyte aggregates caused by the selectin-�binding carbohydrate fucoidan in pig kidneys. Dittrich S, Lippek F, Gratopp A. Grosse-Siestrup C, Lange PE. Buhrer C, Clin Exp Pharmacol Physiol. 2002 Oct 29(10):909-14

26: Protective effects of inhibiting both blood and vascular selectins after stroke and reperfusion. Ruehl ML, Orozco JA, Stoker MB, McDonagh PF, Coull BM, Ritter LS. Neurol Res. 2002 Apr;24(3):226-32.

27: Effects of Fucoidan on chronic renal failure in rats. Zhang Q, Li Z, Xu Z, Niu X, Zhang H. Planta Med. 2003 Jun;69(6):537-41.

28: Fucoidan inhibits the development of proteinuria in active Heymann nephritis. Zhang Q, Li N, Zhao T, Qi H, Xu Z, Li Z. Phytother Res. 2005 Jan;19(1):50-3

29: Effects of C-reactive protein and pentosan polysulphate on human complement activation. Klegeris A. Singh EA. McGerr PL Immunology 2002 Jul;106(3):381-8

NB: * These products are not intended to diagnose, treat, cure, or prevent any disease.

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